(immunology) Involving the contraction of a disease by a person with a decreased susceptibility, such as a person who has been vaccinated to help prevent that disease.
(medicine) The emergence or one or more symptoms of a condition despite medication or other medical treatment.
Characterized by major progress or overcoming some obstacle.
noun
(construction) The penetration of a separating wall or the remaining distance to an adjacent hollow (a crosscut in mining) or between two parts of a tunnel build from both ends; knockthrough.
(military) An advance through and past enemy lines.
(sports) The penetration of the opposition's defence.
Any major progress; such as a great innovation or discovery that overcomes a significant obstacle.
